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MERS-CoV is a member of the coronavirus family of single-stranded RNA viruses. Coronaviruses contain small single-stranded RNA genomes and are the largest known RNA viruses. The coronavirus is a large family of viruses with many members that cause illness in humans. There are four genera of coronavirus: alpha, beta, gamma, and delta. It is the first coronavirus to cause severe morbidity and mortality in humans . Human coronaviruses are mainly associated with respiratory diseases, but other viruses, such as the MERS-CoV, have been associated with a wide range of clinical presentations. After the identification of MERS-CoV, there has been much interest in understanding the epidemiology of this virus in the Arabian Peninsula. The first cases of MERS-CoV were reported in the Sultanate of Oman in September 2012 . The cases spread through multiple linked chains of transmission to the Kingdom of Saudi Arabia in March 2013. The first documented cases were in a 60-year-old man who died of renal failure in 2012, followed by a cluster of cases in a family with direct contact to a sick camel. The first human-to-human transmission of MERS-CoV (from a camels) was reported in a family in the Eastern Province of the Kingdom of Saudi Arabia on May 20, 2013. Since that time, sporadic cases have been reported throughout the Arabian Peninsula, and to Europe, the United States, and even Asia.
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